Incomplete Growth Hormone Secretion with Pituitary Stalk Transection and Syringomyelia

Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome

Growth hormone (GH) is an essential element for normal growth. However, reports of normal growth without GH have been made in patients who have undergone brain surgery for craniopharyngioma. Normal growth without GH can be explained by hyperinsulinemia, hyperprolactinemia, elevated leptin levels, and GH variants; however, its exact mechanism has not been elucidated yet. We diagnosed a female pa...

Luteinizing Hormone Secretion as Affected by Hypophyseal Stalk Transection and Estradiol-17β in Ovariectomized Gilts

The objectives were to determine hypothalamic regulation of pulsatile luteinizing hormone (LH) secretion in female pigs and the biphasic feedback actions of estradiol-17b (E2-17b). In the first study, the minimum effective dosage of E2-17b that would induce estrus in ovariectomized gilts was determined to be 20 mg/kg body weight. In the second study, ovariectomized gilts were assigned randomly ...

Luteinizing hormone secretion as affected by hypophyseal stalk transection and estradiol-17beta in ovariectomized gilts.

The objectives were to determine hypothalamic regulation of pulsatile luteinizing hormone (LH) secretion in female pigs and the biphasic feedback actions of estradiol-17beta (E(2)-17beta). In the first study, the minimum effective dosage of E(2)-17beta that would induce estrus in ovariectomized gilts was determined to be 20microg/kg body weight. In the second study, ovariectomized gilts were as...

Some Effects of Transection of the Pituitary Stalk.

Growth hormone and prolactin secretion of pituitary adenoma.

Tissue culture of 20 pituitary adenomas (four acromegalies, 15 non-functioning tumors, one Forbes-Albright syndrome) was performed with the Maxmow double cover glass assembly. Growth hormone and prolactin in the medium were measured during the culture. Morphological feature in vitro was also compared with that of the original tumor. In chromophobe adenomas of clinically non-functioning, tum...